Animal cell technology: basic & applied aspects, volume 10 : proceedings of the tenth annual meeting of the Japanese Association for Animal Cell Technology, Nagoya, Japan, November 5-8, 1997

Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells but also to ascertain their abilities to be used for industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimization of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins, and the application of animal cells to gene therapy and artificial organs. This Volume gives the readers a complete review of the present state of the art in Japan. The Proceedings will be useful for cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and other disciplines related to animal cell culture, working either in academic environments or in industries of biotechnology and pharmacy. Booknews Held at Nyoga U. in November 1997, the meeting on the newly growing cell biology discipline of animal cell technology attracted 200 participants. The proceedings of the nine symposia, and numerous oral and poster sessions presenting the state-of-the-art in Japan should interest those working in the basic organic sciences and in biotechnology and pharmacy applications. Topics include: glycoengineering, artificial organ and cell therapy, transgenic livestock, gene transfer to cells and tissues of living animals, cell culture for assessment of physiologically functional substances, cost performance for producing biochemicals, applications of human monoclonal antibody, cell characterization and validation, transplantation and artificial organs, transgenic technology, and cytokines and signal transduction. The index spans AchE to zebrafish. Annotation c. Book News, Inc., Portland, OR (booknews.com) Preliminaries......Page 2 Contents......Page 6 Symposium 1: Role of Heparan Sulfate Proteoglycan in Cell Growth and Differentiation......Page 16 Synposium 2: Glycoengineering......Page 22 Symposium 3: Artificial Organ and Cell Therapy......Page 52 Symposium 4:Immunological Manipulation......Page 64 Symposium 5: DT40 Cells as a System of Homologous Gene Recombination......Page 84 Symposium 6: Transgenic Livestock......Page 90 Symposium 7: Transgenic Fish:......Page 106 Symposium 8: Growth, Immortality and Death of Cells in Culture:......Page 122 Symposium 9: Gene Transfer to Cells and Tissues of Living Animals:......Page 134 Oral Session......Page 146 Expression of Recombinant Animal Genes in Cultured Animal Cells......Page 156 Cell Culture Engineering......Page 168 Cost Performance for Producing Biochemicals......Page 180 Establishment of Functional Cell Lines for Production of Biologicals......Page 186 Application of Human Monoclonal Antibody......Page 206 Cell Characterization and Validation......Page 214 Poster Session......Page 238 Expression of Recombinant Animal Genes in Cultured Animal Cells......Page 266 Cell Characterization and Validation......Page 286 Transplantation and Artificial Organs......Page 292 Transgenic Technology......Page 314 Antibody Technology......Page 326 Cytokines and Signal Transduction......Page 338 Cell Culture for Assessment of Physiologically Functional Substances......Page 368 Author Index......Page 400 Subject Index......Page 404