Analytical Profiles of Drug Substances and Excipients, Volume 27 (Profiles of Drug Substances, Excipients, and Related Methodology)

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together in one source. The scope of the series has recently been expanded to include profiles of excipient materials. Read more... Abstract: Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together in one source. The scope of the series has recently been expanded to include profiles of excipient materials Content: Editorial Board Page ii Edited by Page iii Copyright page Page iv Affiliations of Editors and Contributors Pages vii-ix Preface Page xi Harry G. Brittain Arginine Original Research Article Pages 1-32 Amal Shervington, Reema Al-Tayyem Fenoterol Hydrobromide Original Research Article Pages 33-65 Abdulrahman A. Al-Majed Fluconazole Original Research Article Pages 67-113 Alekha K. Dash, William F. Elmquist Flutamide Original Research Article Pages 115-157 Richard Sternal, Niran Nugara Histamine Original Research Article Pages 159-264 Abdullah A. Al-Badr, Hussein I. El-Subbagh Ibuprofen Original Research Article Pages 265-300 John D. Higgins, Timothy P. Gilmor, Stephan A. Martellucci, Richard D. Bruce, Harry G. Brittain Ondansetron Hydrochloride Original Research Article Pages 301-338 Isam Ismail Salem, José M. Ramos López, Antonio Cerezo Galán Sildenafil Citrate Original Research Article Pages 339-376 Adnan A. Badwan, Lina Nabuls, Mahmoud M. Al-Omari, Nidal Daraghmeh, Mahmoud Ashour Mesalamine Original Research Article Pages 377-378 Alekha K. Dash, Harry G. Bnttain Erratum to: Mesalamine (Table 6 was missing) Pages 379-381 Alekha K. Dash, Harry G. Brittain Cumulative Index Pages 383-388 Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories.

Edited by the Associate Director of Analytical Research and Development for the American Association of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together in one source. The scope of the series has recently been expanded to include profiles of excipient materials. Arginine is a white or almost white crystalline powder, obtained as practically odorless crystals.