شیمی تحلیلی: روش‌ها و کاربردها (پیشرفت‌های تحقیقاتی در شیمی)

This title includes a number of Open Access chapters.This collection presents a broad selection of recent research on analytical chemistry, including methods of determination and analysis as applied to plants, pharmaceuticals, foods, proteins, and more. Analytical chemistry is the study of what chemicals are present and in what amount in natur Front Cover 1 Contents 6 Introduction 10 1. Micelle Enhanced Fluorimetric and Thin Layer Chromatography Densitometric Methods for the Determination of (±) Citalopram and its S – Enantiomer Escitalopram 12 2. A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance 27 3. Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate 47 4. Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines 64 5. Quantitative Mass Spectrometric Analysis of Ropivacaine and Bupivacaine in Authentic, Pharmaceutical and Spiked Human Plasma without Chromatographic Separation 79 6. Kinetic Spectrophotometric Determination of Certain Cephalosporins in Pharmaceutical Formulations 93 7. Understanding Structural Features of Microbial Lipases- An Overview 115 8. Significance Analysis of Microarray for Relative Quantitation of LC/MS Data in Proteomics 137 9. Determination of Key Intermediates in Cholesterol and Bile Acid Biosynthesis by Stable Isotope Dilution Mass Spectrometry 165 10. A Dynamic Programming Approach for the Alignment of Signal Peaks in Multiple Gas Chromatography-Mass Spectrometry Experiments 192 11. Solid-Phase Extraction and Reverse-Phase HPLC: Application to Study the Urinary Excretion Pattern of Benzophenone-3 and its Metabolite 2,4-Dihydroxybenzophenone in Human Urine 219 12. A Simple and Selective Spectrophotometric Method for the Determination of Trace Gold in Real, Environmental, Biological, Geological and Soil Samples Using Bis(Salicylaldehyde) Orthophenylenediamine 232 13. Palm-Based Standard Reference Materials for Iodine Value and Slip Melting Point 256 14. Biomedical and Forensic Applications of Combined Catalytic Hydrogenation-Stable Isotope Ratio Analysis 267 15. Identification and Quantitation of Asparagine and Citrulline Using High-Performance Liquid Chromatography (HPLC) 279 16. Searching for New Clues about the Molecular Cause of Endomyocardial Fibrosis by Way of In Silico Proteomics and Analytical Chemistry 290 17. Evaluation of Fructooligosaccharides and Inulins as Potentially Health Benefiting Food Ingredients by HPAEC-PED and MALDI-TOF MS 308 18. Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode 328 19. GC-MS Studies of the Chemical Composition of Two Inedible Mushrooms of the Genus Agaricus 340 20. Structural Analysis of Three Novel Trisaccharides Isolated from the Fermented Beverage of Plant Extracts 348 Content: Micelle Enhanced Fluorimetric and Thin Layer Chromatography Densitometric Methods for the Determination of (+-) Citalopram and its S - Enantiomer Escitalopram. A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance. Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines. Quantitative Mass Spectrometric Analysis of Ropivacaine and Bupivacaine in Authentic, Pharmaceutical and Spiked Human Plasma Without Chromatographic Separation. Kinetic Spectrophotometric Determination of Certain Cephalosporins in Pharmaceutical Formulations. Understanding Structural Features of Microbial Lipases-An Overview. Significance Analysis of Microarray for Relative Quantitation of LC/MS Data in Proteomics. Determination of Key Intermediates in Cholesteroland Bile Acid Biosynthesis by Stable Isotope DilutionMass Spectrometry. A Dynamic Programming Approach for the Alignment of Signal Peaks in Multiple Gas Chromatography-Mass Spectrometry Experiments. Solid-Phase Extraction and Reverse-Phase HPLC: Application to Study the Urinary Excretion Pattern of Benzophenone-3and its Metabolite 2,4-Dihydroxybenzophenone in Human Urine. A Simple and Selective Spectrophotometric Method for the Determination of Trace Gold in Real, Environmental, Biological, Geological and Soil Samples Using Bis(Salicylaldehyde) Orthophenylenediamine. Palm-Based Standard Reference Materials for Iodine Value and Slip Melting Point. Biomedical and Forensic Applications of Combined Catalytic Hydrogenation-Stable Isotope Ratio Analysis. Identification and Quantitation of Asparagine and Citrulline Using High-Performance Liquid Chromatography (HPLC) . Searching for New Clues about the Molecular Cause of Endomyocardial Fibrosis by Way of In Silico Proteomics and Analytical Chemistry. Evaluation of Fructooligosaccharides and Inulins as Potentially Health Benefiting Food Ingredients by HPAEC-PED and MALDI-TOF MS. Preparation, Characterization, and Analytical Application of Ramipril Membrane-Based Ion-Selective Electrode. GC-MS Studies of the Chemical Composition of Two Inedible Mushrooms of the Genus Agaricus. Structural Analysis of Three Novel Trisaccharides Isolated from the Fermented Beverage of Plant Extracts. Index. Analytical chemistry is the study of what chemicals are present and in what amount in natural and artificial materials. Because these understandings are fundamental in just about every chemical inquiry, analytical chemistry is used to obtain information, ensure safety, and solve problems in many different chemical areas, and is essential in both theoretical and applied chemistry. Analytical chemistry is driven by new and improved instrumentation. This collection presents a broad selection of chapters on analytical chemistry, including methods of determination and analysis as applied to pharmaceuticals, foods, proteins, and more Analytical chemistry is the study of what chemicals are present and in what amount in natural and artificial materials. This collection presents a broad selection of articles on analytical chemistry, including methods of determination and analysis as applied to pharmaceuticals, foods, proteins, and more.