Analysis of Genetic Association Studies (Statistics for Biology and Health)

__Analysis of Genetic Association Studies__ is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in __Analysis of Genetic Association Studies__ particularly relevant. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. The organization of this work allows for both casual reference and close study. Front Matter....Pages I-XXII Front Matter....Pages 1-1 Introduction to Probability Theory and Statistics....Pages 3-31 Introduction to Genetic Epidemiology....Pages 33-58 Front Matter....Pages 59-59 Single-Marker Analysis for Unmatched Case-Control Data....Pages 61-93 Single-Marker Analysis for Matched Case-Control Data....Pages 95-120 Bayes Factors for Case-Control Association Studies....Pages 121-150 Robust Procedures....Pages 151-206 Front Matter....Pages 207-207 Haplotype Analysis for Case-Control Data....Pages 209-233 Gene-Gene Interactions....Pages 235-256 Front Matter....Pages 257-257 Population Structure....Pages 259-286 Gene-Environment Interactions....Pages 287-308 Power and Sample Size Calculations....Pages 309-333 Front Matter....Pages 335-335 Genome-Wide Association Studies....Pages 337-349 Front Matter....Pages 351-351 Analysis of Family Data....Pages 353-387 Back Matter....Pages 389-414 Annotation Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. The organization of this work allows for both casual reference and close study