An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma (Advances in Predictive, Preventive and Personalised Medicine, 8)

"This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT) A use-case was developed for hepatocellular carcinoma (HCC) The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes - Font no determinada Front Matter....Pages i-xx Introduction....Pages 1-7 The Digital Patient Model and Model Guided Therapy....Pages 9-19 Hepatocellular Carcinoma and Patient Assessment....Pages 21-32 Imaging in Hepatocellular Carcinoma: Radiologic Assessment....Pages 33-44 Imaging in Hepatocellular Carcinoma: PET/CT....Pages 45-51 Personalized Chemotherapy for Hepatocellular Carcinoma....Pages 53-60 Surgical Treatment for Hepatocellular Carcinoma....Pages 61-68 Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies....Pages 69-76 Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies....Pages 77-83 Minimally Invasive Therapies for Hepatocellular Cancer: Catheter-Directed Therapies....Pages 85-91 Radiation Oncology in the Treatment of Hepatocellular Carcinoma....Pages 93-102 Design of an IT System for Hepatocellular Carcinoma....Pages 103-117 Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma....Pages 119-127 Back Matter....Pages 129-130 Leonard Berliner, Heinz U. Lemke, Editors. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.