Amyloid and Amyloidosis 1990: VIth International Symposium on Amyloidosis August 5–8, 1990, Oslo, Norway (Ecological Studies)

Both scientifically and socially the Vlth International Symposium on Amyloidosis, August 5 - 8, 1990 in Oslo was a great success. There were three and a half intensive days. It started with the Opening Ceremony, particularly highlighted with the Norway-Norway multi media show by David Cochron, and ended with a visit to the Edvard Munch museuro and the Farewell Salmon­ Dinner on the evening of August 8 (not to forget the "happy birthday" song for Dorothea Zucker-Franklin at the breakfast table the following morning). In between was the intellectual penetration into the science of amyloidosis and amyloid proteins, and a deepening of many friendships among young and old "amyloidologists", together with some of the cultural and historical features of Oslo and Norway. Among the numerous Ietters of thanks and gratitude that we have received, the senior organizer of the previous meeting, Takashi lsobe said it briefly and eloquently: "You have overwhelmed us, you have performed a drama with joy and cheer, you have hosted so nicely with lovely secretariat, you have arranged impressive hospitality in every respect, you certainly did for all of us" Now we are left with the proceedings book for the three coming years until the next symposium in Kingston, Canada, which will be organized by Drs. Robert Kisilevsky and Thomas Muckle from the Department of Pathology at Queens University in 1993. The scientific contributions herein cover all the sessions of the meeting. Front Matter....Pages i-xxviii Welcome!....Pages 1-3 Elliott F. Osserman in Memoriam....Pages 5-5 The 1990 Guidelines for Nomenclature and Classification of Amyloid and Amyloidosis....Pages 7-11 The Human Serum Amyloid a Genes and their Regulation by Inflammatory Cytokines....Pages 13-19 Genetic Isofocusing Variant of Human Serum Amyloid A....Pages 20-23 Sequence Analysis of a Third Human SAA Gene....Pages 24-27 Human Serum Amyloid-A Protein: Variability Demonstrated by CDNA Sequencing and Expression Studies....Pages 28-31 Abyssinian Cat Model of AA Amyloidosis: SAA Gene Analysis....Pages 32-35 Mink Serum Amyloid a Protein — Expression and Primary Structure of Amyloidogenic and Non-Amyloidogenic Isotypes....Pages 36-39 Primary Structure of Two Rabbit Serum Amyloid a Proteins (SAA) Based on cDNA Sequence....Pages 40-43 Biosynthesis and Processing of SAA by Mouse L-Cells Transfected with the Human SAAg9 Gene....Pages 44-47 Regulation of serum amyloid A (SAA) synthesis in Hep 3B cells by cytokines and corticosteroids.....Pages 48-51 Regulation of SAA Synthesis by Cytokines in a Human Hepatoma Cell Line.....Pages 52-56 SAA Secretion from Cytokine-Stimulated Human Hepatoma Cells Requires HDL....Pages 57-61 Interferon Alfa Induce Tnf Elevations in vivo. Correlation with Other Acute Phase Reactants.....Pages 62-65 Acute Phase Protein, Serum Amyloid A, Inhibits IL-1- and Tnf-Induced Fever and Hypothalamic Pge 2 in Mice....Pages 66-67 Human Recombinant TNF-α and Poly I.Poly C Induce SAA and Enhance Amyloidosis in Hamster.....Pages 68-70 The Physiology of the Acute Phase Serum Amyloid a (SAA) Response in Mice....Pages 71-74 Mouse SAA 3 : Detection in Mouse Tissues with Specific Antibody....Pages 75-78 Generation and Use of Site-Specific Antibodies Against SAA.....Pages 79-82 The N-Terminus is the Lipid-Binding Site of SAA: Supporting Evidence by MoAbs....Pages 83-86 Epitope Mapping of Amyloid-A Protein Using Monoclonal Antibodies....Pages 87-90 Reactive (AA) Amyloidosis in a 14 Year Old with No Predisposing Disease....Pages 91-94 Induction of Amyloidosis in Mice: Preparation of Active Azocasein (AZO) and Effect of Endotoxin (LPS).....Pages 95-98 Serum Amyloid A (SAA) Induction in the Serum High Density Lipoproteins of the Syrian Hamster....Pages 99-102 The Complete Primary Structure of Bovine Serum Amyloid Protein a (SAA) and of Tissue Amyloid Fibril Protein a (AA) Subspecies....Pages 103-106 Degradation of SAA in Amyloid Fibrils by Elastase.....Pages 107-110 Evolutionary Aspects of Protein SAA....Pages 111-114 Strain Specific Variation in Expression of Novel Mouse apo-SAA Isoforms....Pages 115-118 SAA Isotypes in Patients with Secondary Amyloidosis....Pages 119-123 Differential Regulation of Human Serum Amyloid a Isoforms....Pages 125-128 The Effect of SAA-Derived Fragment — SAA 2–82 — On Platelet Aggregation....Pages 129-132 Serum Amyloid A, an Acute Phase Protein, Inhibits Platelet Activation....Pages 133-134 Serum Amyloid A (SAA)-Related Peptide Isolated from Synovial Fluid Modulates Superoxide Production by Human Neutrophils.....Pages 135-138 Antiplatelet Aggregation Activity of Serum Amyloid a (SAA) Related Peptides....Pages 139-142 Effect of Purified Serum Amyloid a On Growth and Differentiation of Transformed Cells....Pages 143-145 Primary Systemic Amyloidosis (AL) in 1990.....Pages 147-152 Comparison of the Amino Acid Sequences of Ten Kappa I Amyloid Proteins for Amyloidogenic Sequences....Pages 153-156 Characterization of a kAL Protein and Two Amyloidogenic kBJP in three Cases of Immunoglobulin Amyloidosis....Pages 157-160 Biclonality in Amyloidosis Patient MAL: One Clone Produncing an Amyloidogenic, the Other a Non-Amyloidogenic Kappa L-Chain — AL Amyloidosis....Pages 161-164 Complete Amino-Acid Sequence of a Kappa Light Chain Fragment Isolated from the Urine of Amyloidosis Patient MAL....Pages 165-168 Comparative Studies of Two AL Chains of Kappa-III Light Chain Origin with and without Attached Carbohydrate (AL So124 and AL 700)....Pages 169-172 Structural Studies of Two Carbohydrate-Containing AL Chains (Λll) AL NØV And AL MC.....Pages 173-176 Complete Amino-Acid Sequence of AL-Bence-Jones Protein POL of the Lambda I Subclass....Pages 177-180 Complete Amino-Acid Sequence of AL-Lambda 1.1 Bence-Jones Protein EZI....Pages 181-184 Complete Amino-Acid Sequence of a Lambda Amyloid Fibril Protein Isolated from the Liver of Amyloidosis Patient DIA....Pages 185-188 Systemic AL Amyloidosis in a Cat....Pages 189-192 Experimental Production of Human Amyloidosis AL....Pages 193-196 AL Amyloid, L-Chain And L & H-Chain Deposition Diseases: Comparison of Ig Synthesis and Tissue Deposition.....Pages 197-200 Gene Rearrangement Studies in the Diagnosis Of ‘Primary’ Systemic Amyloidosis and Nodular Localized Cutaneous Amyloidosis....Pages 201-202 Clinicopathologic Correlations in 109 Patients with Systemic Amyloidosis Studied by Immunocytochemistry....Pages 203-206 Quantification of Non-Light Chain Amyloid Precursors and Acute Phase-Related Proteins in AL-Amyloid Sera.....Pages 207-210 Incidence and Epidemiology of Primary Systemic Amyloidosis (AL) in Olmsted County, Minnesota: 1950 Through 1989....Pages 211-214 Low Incidence of AL Amyloidosis in Japan....Pages 215-218 Clinical Indications of Systemic Amyloidosis in Myeloma Patients....Pages 219-222 Bence Jones Proteinemia Without Bence Jones Proteinuria in AL Amyloidosis....Pages 223-226 Systemic Amyloidosis and Monoclonal Gammopathy in Three Italian Siblings : A Familian Case of AL-Amyloidosis?....Pages 227-230 Primary Systemic Amyloidosis (AL): A Randomized Trial of Colchicine vs. Melphalan And Prednisone vs. Melphalan, Prednisone, and Colchicine.....Pages 231-234 Response Rates and Survival in Primary Systemic Amyloidosis....Pages 235-238 Urinary Protein Patterns Predict Survival in Primary Systemic Amyloidosis (AL)....Pages 239-242 ß 2 -Microglobulin Predicts Survival in Primary Systemic Amyloidosis (AL)....Pages 243-246 Cutaneous Amyloidosis in a Horse. Partial Amino Acid Sequence Analysis of an Equine Immunoglobulin-Lambda Light Chain....Pages 247-248 Experimental Amyloid Casts in Mice Induced by Injection of a Human Bence Jones Protein....Pages 249-249 Common Elements in Amyloidosis....Pages 251-253 Metabolic Studies of Radioiodinated Serum Amyloid P Component in Normal Subjects and Patients with Systemic Amyloidosis....Pages 254-257 Structural and Functional Studies of Serum Amyloid P Component....Pages 258-259 Quantification of Amyloid P-Component in Multiple Tissues of Patients with Primary and Familial Amyloidois....Pages 260-263 A Primed State Exists in vivo Following Regression of Murine AA Amyloidosis....Pages 264-267 Serum Amyloid P-Component (SAP) Regulation by Sex-Steroids in Rats: Compared with C-Reactive Protein (CRP)....Pages 268-271 Acute Phase Protein Response to Collagen Induced Arthritis in Mice....Pages 272-275 An Attempt to Study the Role of Serum Amyloid P Component in the Formation of Amyloid Deposits in a Transgenic Mouse Model of Familial Amyloidotic Polyneuropathy....Pages 276-279 Differential Regulation of SAP Gene Expression in Syrian and Armenian Hamsters.....Pages 280-283 Isolation of cDNA Clones & Expression Analyses for Rat Serum Amyloid P (SAP) Component....Pages 284-287 Isolation of a 16 KD Fraction with Extremely High AEF Activity....Pages 288-291 Amyloid Enhancing Factor (AEF) — Induced Amyloidosis Lacks Inflammatory Reaction....Pages 292-295 The Tissue Origin of Amyloid Enhancing Factor Determines its Ability to Induce SAA Gene Expression....Pages 296-299 PMSF-Sensitive Serine Esterase-Activity and Fibril-Derived Amyloid Enhancing Factor (FAEF)-Activity in Hamster are not Related....Pages 300-302 Induction of Amyloid Deposition by Subfractions of the Amyloid Enhancing Factor Extracted from Brain of Patients with Alzheimer’s Disease....Pages 303-306 Isolation of Amyloid Ehancing Factor (AEF)....Pages 307-310 Effects of Amyloid Enhancing Factor on in vitro Kupffer Cells....Pages 311-314 Macromolecular Characteristics of AA Type Amyloid Associated Polysaccharides from Human Liver, Kidney and Spleen with AA Amyloid Secondary to Rheumatic Disease....Pages 315-318 Heparan Sulfate Accumulation in the Beta-Amyloid Protein Containing Lesions of Down’s Syndrome Occurs Prior to the Appearance of Fibrillar Amyloid....Pages 319-322 Rapid Synthesis of cRNA Probes for SAA, SAP and Heparan Sulfate Proteoglycan mRNAs by Transcription of Polymerase Chain Reaction Generated Templates....Pages 323-328 Basement Membrane Components in Addition to HSPG are Present in Murine AA Amyloid Deposits....Pages 329-333 The Basement Membrane Form of Heparan Sulfate Proteoglycan is Part of Human IAPP Amyloid Deposits in the Islets of Langerhans....Pages 334-337 Isolation and Characterisation of the Integral Glycosaminoglycan Constituents of Human AA and AL Amyloid Fibrils....Pages 338-341 Basement Membrane Components and Protein AA in Renal Amyloid Deposits....Pages 342-345 High Molecular Weight Polysaccharides in Familial Cardiac Amyloid of Danish Origin Related to Transthyretin Met 111....Pages 346-349 Point Mutation in Autosomal Dominant Forms of Amyloidosis....Pages 351-356 Perturbation of processing of cystatin C in monocytes from patients with hereditary cystatin C amyloid angiopathy....Pages 357-360 Molecular Biology of Hereditary Cystatin C Amyloid Angiopathy in Iceland....Pages 361-364 Cerebral Amyloid Angiopathy Associated with Cerebral Hemorrhage with the Deposition of Cystatin C: Study on Japanese Cases....Pages 365-368 Several β 2 -Microglobulin Fragments Identified in an Amyloidoma in a Patient with Long-Term Hemodialysis....Pages 369-372 Clinical Evaluation of Osteoarthropathy in 43 Patients on Haemodialysis, Using Cuprophane Membranes for ≥ 5 Years....Pages 373-376 β 2 -Microglobulin-Derived Amyloid and Calcium in Long-Term Dialysis Patients....Pages 377-380 In Vivo Metabolism of a Mutant Apolipoprotein A-I (ARG-26) Associated with Hereditary Amyloidosis....Pages 381-384 New USA Family has Apolipoprotein AI (ARG26) Variant....Pages 385-388 Molecular Genetic Study of Mouse Senile Amyloidosis....Pages 389-392 Fluorometric Examination of Tissue Amyloid Fibrils in Murine Senile Amyloidosis: Use of the Fluorescent Indicator, Thioflavine T....Pages 393-396 The Low Leukocyte (LLC) Mouse, a Second Model of “Senescence -Accelerated” Amyloidosis Associated with Apolipoprotein All Pro 5 →GLN; Prevalence of this Substitution Among Inbred Strains of Mice....Pages 397-401 Age-Related Amyloid in the Aorta....Pages 402-404 Complete Primary Structure of Amyloid Protein in Finnish Hereditary Amyloidosis. Identification of a New Type of Amyloid Protein Derived from Variant (ASN-187) Gelsolin....Pages 405-408 Polymerization of Gelsolin Variant Fragment in Tissue Causes Familial Amyloidosis, Finnish Type (FAF)....Pages 409-413 Gelsolin-Related Amyloidosis. Immunohistochemical Studies in Finnish Hereditary Amyloidosis with Antibodies to a Synthetic Dodecapeptide of the Amyloidogenic Region of Gelsolin....Pages 414-417 Familial Amyloidosis, Finnish Type....Pages 418-422 Shared Gelsolin Antigenicity Between Familial Amyloidosis Finnish Type (FAF) and One form of Familial Lattice Corneal Dystrophy (LCD) with Polyneuropathy from the United States....Pages 423-425 Polypeptide Hormones and Amyloid....Pages 427-432 Islet amyloid polypeptide (IAPP): structure of its cDNA and gene and the identification of species differences of importance for islet amyloid formation.....Pages 433-436 Human Islet Amyloid Polypeptide (IAPP): Identification in Human Pancreas, Establishment of Radioimmunoassay, and its Response to Physiological Stimulation....Pages 437-440 Rat Islet Amyloid Polypeptide (IAPP): Isolation and Sequence Determination, Immunohistochemical Study, and its Secretion from Pancreas....Pages 441-444 Factors Affecting Diabetogenesis and Amyloidogenesis are Provided by Studies of IAPP in the Dog and Cat....Pages 445-448 Islet Amyloid Polypeptide: Synthetic Peptides for Study of the Pathogenesis of Islet Amyloid....Pages 449-452 Intracellular Formation of Amyloid Fibrils in B-Cells of Human Insulinoma and Pre-Diabetic Monkey Islets....Pages 453-456 A Comparative Study Between Human B-Cell Insulin and Islet Amyloid Polypeptide (IAPP) Storage and Amyloid Deposition in Type 2 Diabetes Mellitus and in Non-Diabetics....Pages 457-461 Pancreatic Islet Amyloid in the Degu Is Derived from Insulin....Pages 462-465 Isolated Atrial Amyloid Deposits. Immunochemical Evidence for the Presence of Polypeptides with Molecular Weights Higher and Lower than Atrial Natriuretic Peptide ANP....Pages 466-469 Raised Prevalence of Isolated Atrial Amyloidosis in Chronic Heart Disease....Pages 470-473 Isolated Atrial Amyloidosis. Increased Frequency in Patients with Congestive Cardiac Failure....Pages 474-476 Characterization of Molecular forms of Calcitonin in Amyloid Fibrils from Medullary Carcinoma of the Thyroid....Pages 477-480 Pathofibrillogenesis and Amyloid Proteins....Pages 481-486 The Sulphate and Chloride Ions have Different Effects on the Structure of AA Amyloid Fibrils....Pages 487-492 Kinetic Properties of Amyloid Fibril Polymerization in Vitro....Pages 493-496 In Vitro Assembly of Murine Amyloid a Protein, Two Murine Serum Amyloid a Proteins, and Normal Human Transthyretin to form Amyloid-Like Fibrils....Pages 497-500 Secondary Structure Changes in Mutant Transthyretins after Proteolysis by Neutrophilic Serine Proteases....Pages 501-504 Production of Amyloidogenic Peptides from Human Immunoglobulin Light (L)-Chains....Pages 505-510 Predominance of One SAA Isotype (SAAI) in Human Reactive Amyloid....Pages 511-514 A Histochemical Model of the Amyloid Fibril....Pages 515-518 High Molecular Weight Proteins, Sensitive to Collagenase Digestion are Intimate Constituents of Amyloid Deposits....Pages 519-522 Intraperitoneal Amyloid Formation by Amyloid Enhancing Factor Rich Macrophages in Ascitic Fluid....Pages 523-526 Histochemically Recognizable Changes of Amyloid Fibrillogenic Macrophages....Pages 527-530 Ultrastructural Aspects of Cell Membrane in AA-Amyloidogenesis....Pages 531-534 Amyloid Fibril Formation in the Rough Endoplasmic Reticulum of Plasma Cells from a Patient with Localized Aλ Amyloidosis....Pages 535-538 A Comparative Study of Amyloid Formation and Resorption Using Immunoelectron Microscopy....Pages 539-542 A Histochemical, Immunohistochemical, Ultrastructural and Immunoelectron Microscopical Characterization of Cerebrovascular Amyloid and Diffuse Plaques in Autopsied Aged Dogs....Pages 543-546 Increased Binding of Acute Phase Lipoproteins by Peritoneal Macrophages (MØs) in Mice....Pages 547-550 Characterization of Non-AA Proteins in Amyloid Fibrils Obtained from a Cow with Chronic Infection....Pages 551-554 Compositional Analyses of Amyloid Fibrils....Pages 555-558 Intratumour Amyloidosis in Primary and Metastatic Nasopharyngeal Carcinoma: An Immunohistochemical and Ultrastructural Study....Pages 559-564 Intratumour Amyloidosis in Carcinoma of the Cervix....Pages 565-568 Molecular Biology of Amyloidogenesis in the Transthyretin Related Amyloidoses....Pages 569-574 Studies on the Molecular Arrangement in Transthyretin-Related Familial Amyloidotic Polyneuropathy Fibrils....Pages 575-578 X-Ray Crystal Structure of the Met-30 Variant of Human Prealbumin (Transthyretin)....Pages 579-582 Disulfide Bond Formation of Transthyretin (TTR) as Possible Initial Step of Familial Amyloid Polyneuropathy (FAP)....Pages 583-586 Structure of Transthyretin Molecules in Amyloid Fibrills from the Vitreous Body in Individuals with the Met30 Mutation....Pages 587-590 Formation of Fibrils by Normal Transthyretin and Synthetic Transthyretin Fragments In Vitro ....Pages 591-594 First Turkish Family with FAP has Homozygous Met 30 TTR....Pages 595-598 A New Transthyretin Variant Associated with Familial Amyloidotic Polyneuropathy in an Italian Kindred....Pages 599-602 Clinical Characterization of a New TTR Variant in an Italian Family: TTR ALA 49....Pages 603-606 A TTR Acidic Variant DNA Analysis Of Homozygous and Heterozygous Individuals....Pages 607-610 ASN 90 is the Variant TTR in an Italian FAP Kinship....Pages 611-614 Frequency of the Position 122 (VAL→ILE) Variant Transthyretin Gene in Blacks Without Amyloidosis....Pages 615-617 Variant Transthyretins In Familial Amyloidotic Polyneuropathy (FAP)....Pages 618-621 Three Novel Variants of Transthyretin Identified in Three Japanese Kindreds with Familial Amyloidotic Polyneuropathy....Pages 622-626 A Possible New Transthyretin Genetic Variant in a Family with Cardiac Amyloidosis....Pages 627-630 Structural Studies of Transthyretin and Related Fragments Obtained from a Swedish Patient (V-ÅS 280) with Senile Systemic Amylodosis....Pages 631-634 The transthyretin cDNA sequence is normal in transthyretin-derived senile systemic amyloidosis....Pages 635-638 A Recombinants System for Production of Variant Type Human Transthyretin(TTR)....Pages 639-642 Assessement of Structure and Binding Capacities of Secreted Mutant Transthyretins by an E. Coli System....Pages 643-646 Structure and Function of Recombinant Human Transthyretin....Pages 647-650 Detection of Variant Transthyretin Genes by Restriction Analysis of PCR-Amplified Genomic DNA....Pages 651-654 Myelin P2 Protein in Transthyretin (Ser-84) Vitreous Amyloid....Pages 655-658 Cloning and Trimming of the TTR-cDNA Gene by PCR....Pages 659-662 Pathological Similarity of Transgenic Mice Carrying the Human Mutant Transthyretin Gene to Human Familial Amyloidotic Polyneuropathy (FAP) Type I....Pages 663-666 Prealbumin type cerebral amyloid angiopathy in familial amyloid polyneuropathy....Pages 667-670 Amyloid Localized to the Tenosynovium at Carpal Tunnel Release: Immunohistochemical Identification of Amyloid Type....Pages 671-674 Reevaluation of 134 Patients with Familial Amyloidotic Polyneuropathy (FAP) in Japan, Kumamoto Focus....Pages 675-678 Sympathetic Skin Response in Familial Amyloid Polyneuropathy....Pages 679-682 Extrinsic and Intrinsic Nerve Lesions of the Intestine in Type I Familial Amyloid Polyneuropathy....Pages 683-686 Sex Differences and Age-Dependent Penetrance in FAP-Type I....Pages 687-690 Parental Transmission and Age-of-Onset in Familial Amyloidotic Polineuropathy (Portuguese Type)....Pages 691-693 Anticipation of Age-of-Onset in Familial Amyloidotic Polineuropathy (Portuguese Type)....Pages 694-697 Sporadic, Late-Onset Case of Familial Amyloid Polyneuropathy Type I (Andrade) — A Clinicopathological Study....Pages 698-701 Familial Amyloidosis without Transthyretin (TTR) Involvement: an Unusual Presentation....Pages 702-705 Mechanisms of Amyloid Fibril Formation in Alzheimer’S Disease and Other Dementias....Pages 707-712 Amyloid ß-Protein Deposition as a Seminal Pathogenetic Event in Alzheimer’s Disease....Pages 713-717 Proteolytic Processing of ß-Amyloid Protein-Related Synthetic Peptides and the ß-Protein Precursor by a Protease Purified from Alzheimer’s Disease Brain....Pages 718-721 Immunoreactivity of Alzheimer Amyloid Precursor Protein (APP) Specific Antisera with Platelet Granule Constituents....Pages 722-725 Site of Formation of Beta-Protein Amyloid Fibrils....Pages 726-731 A Search for Vascular Amyloid Using A4 Amyloid Antibody Immunostain in CAA (Classic Methods) Negative Alzheimer’s Cases....Pages 733-736 A variant of Gerstmann-Sträussler-Scheinker disease with ß -protein epitopes and dystrophic neurites in the peripheral regions of PrP -immunoreactive amyloid plaques....Pages 737-740 Antigenic Heterogeneity of Cerebral Amyloid Deposits in Alzheimer’s Disease....Pages 741-744 Systemic Vascular Amyloidosis Associated with Alzheimer’s Disease....Pages 745-748 Pathological Changes in Hereditary Cerebral Hemorrhage with Amyloidosis — Dutch Type....Pages 749-752 Hereditary Cerebral Hemorrhage with Amyloidosis — Dutch Type....Pages 753-756 Peripheral Distribution of a Dermatan Sulfate Proteoglycan (Decorin) in Amyloid Plaques and their Presence in Neurofibrillary Tangles of Alzheimer’S Disease....Pages 757-760 Choroid Plexus Amyloid....Pages 761-764 New Images of Clinical Amyloidosis....Pages 765-770 Scintigraphic Imaging of Amyloidosis with 123 Iodine Serum Amyloid P Component....Pages 771-774 Longtime Follow up of Patients with Al-Amyloidosis with MRI....Pages 775-776 Detection of Autonomic Dysfunctions in Patients with Familial Amyloidotic Polyneuropathy (FAP) by Laser Doppler Method....Pages 777-780 Non-Invasive in Vivo Detection of Ab-Amyloidosis Using its Radiolabelled Precursor Protein....Pages 781-784 Cardiac Involvement in Secondary Amyloidosis....Pages 785-788 Imaging Hereditary Amyloidosis of Ostertag....Pages 789-792 Computer-Aided Immunohistochemical Quantitation of Amyloid in Renal Biopsies....Pages 793-796 Abdominal Fat Biopsy for Characterization of the Major Amyloid Fibril Proteins by Amino Acid Sequence Analysis....Pages 797-800 Beta-2-Microglobulin Does Not Deposit in Abdominal Fat Tissue of Long-Term Hemodialysis Patients....Pages 801-804 Histopathologic Classification, Clinical Characteristics and Survival of 18 Patients with Inconclusive Clinical Data to Identify the Aa or Al Type of their Systemic Amyloidosis....Pages 805-808 Immunohistochemical Detection of Amyloid AA in Formaline-Fixed Paraffine-Embedded Rectal Biopsies with the Monoclonal Anti-Human Saa Antibody Reu.86.2....Pages 809-812 Long Survival in Patients with Al Amyloidosis....Pages 813-816 Secondary Systemic Amyloidosis (AA): Response and Survival in 64 Patients....Pages 817-820 Renal Manifestations of Amyloidosis Complicated with Rheumatoid Arthritis....Pages 821-824 Crp and SAA Serum Levels in Chronic Active Hepatitis....Pages 825-826 Serum Amyloid a and C-Reactive Protein in the First 4 Weeks after Liver Transplantation....Pages 827-830 Differential Influence of Glucocorticoids on CRP and SAA Serum Levels in Rheumatoid Arthritis and Polymyalgia Rheumatica....Pages 831-834 Ocular Microangiopathy in Familial Amyloidotic Polyneuroapthy (FAP) Type I....Pages 835-838 Spectral Analysis of R-R Variability in Familial Amyloidotic Polyneuropaty, Andrade Type....Pages 839-842 Microalbuminuria in Patients with Familial Mediterranean Fever....Pages 843-846 Dopamine-ß-Hydroxylase in Familial Mediterranean Fever....Pages 847-849 A Multicentric Study on Hemodialysis Amyloid Osteoarthropathy in 747 Dialysis Patients....Pages 851-854 Renal Transplantation in Renal Amyloid End-Stage Disease....Pages 855-858 Effect of Continuous Colchicine Treatment in Familial Mediterranean Fever (F.M.F)....Pages 859-862 Treatment of Amyloidosis Associated Diarrhea with a Somatostatin Analogue....Pages 863-865 Gastrointestinal Malabsorption in Familial Amyloidotic Polyneuropathy (FAP): Ursodeoxycolic Acid Absorption Test....Pages 866-869 The Prevalence, Importance and Significance of Amyloidosis with Rheumatic Diseases in Turkey....Pages 870-873 Cyclosporin Reduces the Incidence of Amyloid Disease in Casein Treated Mice....Pages 874-882 Report of Special Session on Bioassays and Standardization of Amyloid Proteins and Precursors....Pages 883-889 Identification of apo-SAA isoforms in man and mouse....Pages 890-893 Normal Lipoproteins Inhibit Binding of SAA-Rich Lipoproteins to Polyvinylchloride Surfaces....Pages 894-897 Monoclonal Antibody Based ELISA for Human SAA....Pages 898-901 Serum Amyloid P Component in Chronic Renal Failure and Dialysis....Pages 902-905 Monoclonal Antibodies to Human Serum Amyloid P-Component....Pages 906-910 Screening with Monoclonal Anti Beta-Protein Antibody for Immuno-Reactivity in the Sera of Patients with Alzheimer’s Disease....Pages 911-914 Symposium Day 1: Overview....Pages 915-916 Amyloidosis: Molecular Insights and Cellular Blindspots....Pages 917-920 Summary of Day 3....Pages 921-922 Back Matter....Pages 923-937