American Herbal Products Association’s Botanical Safety Handbook, Second Edition

Access to accurate, evidence-based, and clinically relevant information is essential to anyone who uses or recommends herbal products. With input from some of the most respected experts in herbal and integrative medicine, this completely revised edition of the American Herbal Products Association’s **Botanical Safety Handbook** reviews both traditional knowledge and contemporary research on herbs to provide an authoritative resource on botanical safety. The book covers more than 500 species of herbs and provides a holistic understanding of safety through data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. For each species, a brief safety summary is provided for quick reference, along with a detailed review of the literature. Easily understood classification systems are used to indicate the safety of each listed species and the potential for the species to interact with drugs. Enhancements to the Second Edition include: * Classification of each herb with both a safety rating and a drug interaction rating * More references listed for each individual herb, vetted for accuracy * Specific information on adverse events reported in clinical trials or case reports * Safety-related pharmacology and pharmacokinetics of each herb, including drug interactions * Additional information on the use of herbs by pregnant or lactating women * Toxicological studies and data on toxic compounds Representing the core of the botanical trade and comprising the finest growers, processors, manufacturers, and marketers of herbal products, the mission of the AHPA is to promote the responsible commerce of herbal products. **The American Herbal Products Association Botanical Safety Handbook, Second Edition** ensures that this vision is attained. The book will be a valuable reference for product manufacturers, healthcare practitioners, regulatory agencies, researchers, and consumers of herbal products. Botanical Safety Handbook - Second Edition......Page 1 Dedication......Page 3 Contents......Page 5 Preface to the First Edition......Page 7 Preface......Page 9 Acknowledgments......Page 11 Financial Support......Page 13 Editors......Page 15 Expert Advisory Council......Page 17 Introduction......Page 19 Organization of Data......Page 25 Disclaimer......Page 29 Literature Cited......Page 30 Review Details......Page 31 Literature Cited......Page 32 Review Details......Page 33 Quick Reference Summary......Page 34 Review Details......Page 35 Literature Cited......Page 36 Quick Reference Summary......Page 37 Review Details......Page 38 Literature Cited......Page 39 Quick Reference Summary......Page 40 Literature Cite......Page 41 Quick Reference Summary......Page 42 Literature Cited......Page 43 Review Details......Page 44 Quick Reference Summary......Page 45 Review Details......Page 46 Literature Cited......Page 49 Literature Cited......Page 52 Literature Cited......Page 53 Review 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Chow......Page 971 Review Details......Page 972 Literature Cited......Page 973 Mechanism of Action......Page 974 Berberine......Page 975 Mechanism of Action......Page 976 Literature Cited......Page 977 Adverse Effects......Page 978 Literature Cited......Page 979 Adverse Effects......Page 980 Literature Cited......Page 981 Mechanism of Action......Page 982 Salicylates......Page 983 Literature Cited......Page 984 Listed Herbs......Page 985 Thujone......Page 986 Listed Herbs......Page 987 Literature Cited......Page 988 Listed Herbs......Page 989 Adverse Effects......Page 990 Literature Cited......Page 991 Adverse Effects......Page 992 Literature Cited......Page 993 Adverse Effects......Page 994 Emmenagogues and Uterine Stimulants......Page 995 Listed Herbs......Page 996 Adverse Effects......Page 997 Literature Cited......Page 998 Mechanism of Action......Page 999 Literature Cited......Page 1000 CY P-Based Drug Interactions......Page 1001 Differences in Human, Animal, and In Vitro Study Findings......Page 1002 Literature Cited......Page 1003 Literature Cited......Page 1004 Literature Cited......Page 1005 Contraindicated Herb Lists and Botanical Safety Classifications......Page 1007 Safety of Herbs in Pregnancy and Lactation......Page 1008 Emmenagogues, Uterine Stimulants, Abortifacients, and Partus Preparator......Page 1009 Nervous System Stimulants or Depressants......Page 1010 Literature Cited......Page 1011 Safety Class 2b: Not To Be Used during Pregnancy......Page 1013 Interaction Class B: Herbs for Which Clinically Relevant Interactions Are Biologically Plausible......Page 1015 Interaction Class C: Herbs for Which Clinically Relevant Interactions Are Known to Occur......Page 1016 Index......Page 1017 Safety and Interaction Classifications......Page 1061 The American Herbal Products Association is the only national trade association devoted to herbal issues. Representing the core of the botanical trade, comprised of the finest growers, processors, manufacturers and marketers of herbal products, their mission is to promote the responsible commerce of herbal products. This second edition includes a drug interaction rating classification and presents specific information on drug interactions as well as use in pregnant and lactating women. The text also provides information on any adverse effects, pharmacology and pharmacokinetics, as well as toxicological studies Reviews both traditional knowledge and contemporary research on herbs, providing data to guide manufacturers and consumers in the safe utilization of herbal products. Contributors cover more than 500 species of herbs and use a classification system to indicate the safety of each listed species and the potential for drug interactions. --From publisher description