Advances in Virus Research, Volume 69 (Advances in Virus Research) (Advances in Virus Research)

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology. The Innate Antiviral Response: New Insights Into A Continuing Story 2 Introduction 0 Interferons 0 Antiviral Effect of IFN: Induction of ISG 0 Induction of Type I IFN Genes: Transcription Factors of the IRF Family 0 Pathogen Recognition Systems 0 Toll-Like Receptors 0 Negative Regulators of TLR 0 Cytoplasmic CARD Receptors 0 TLR9 Independent Recognition of dsDNA 0 Virus Recognition by Cellular Sensors 0 Antigen Presenting Cells: Dendritic Cells 0 IFN-Mediated Cross Talk Between Innate and Acquired Immune Response 0 Viral Evasion of the Interferon Response 0 Inhibition of Type I IFN Induction 0 Inhibition of Type I IFN Signaling 0 Conclusions and Perspectives 0 Acknowledgments 0 References 0 Apoptosis During Herpes Simplex Virus Infection 0 Background 0 Apoptosis 0 Herpesviruses and Apoptosis 0 Herpes Simplex Virus Life Cycle 0 HSV-1's Modulation of Apoptosis 0 Prevention of Apoptosis by HSV-1 0 Wild-Type Virus 0 The Prevention Window 0 Viral Antiapoptotic Factors 0 ICP4 0 ICP27 0 US3 0 ICP22 0 gD 0 gJ 0 LAT 0 Cellular Genes 0 Bcl-2 0 NF-kappaB 0 Apoptosis Induction 0 ICP0 Gene Expression Is a Viral Apoptotic Trigger 0 Requirement for Caspase 3 0 Summary and Unanswered Questions 0 Cell-Type Differences 0 Oncoapoptosis 0 Immortalized Vs Transformed Cells 0 Summary and Unanswered Questions 0 Apoptosis and HSV-1-Associated Disease 0 Ocular Disease 0 Encephalitis 0 Summary and Unanswered Questions 0 Conclusions and Perspectives 0 Acknowledgments 89 References 0 The Baculoviruses Occlusion-Derived Virus: Virion Structure and Function 0 Introduction 0 Baculoviruses 0 Origin of Baculoviruses 0 Baculovirus Occlusion 0 The Baculovirus Life Cycle 0 Virus Entry into the Midgut 0 The Structure of OBs 0 Infection of the Midgut Epithelium 0 Infection of Tissues Beyond the Midgut 0 Cytopathology and Virion Phenotypes 0 The Early Phases 0 The Budded Virus 0 The Occlusion-Derived Virus 0 Multiple Occlusion and Bypass of Midgut Cell Replication 0 ODV Nucleocapsid Proteins 0 The Nucleocapsid 0 Nucleoprotein Core 0 Nucleocapsid Proteins Involved in DNA Packaging 0 DNA Replication Proteins in the Nucleocapsid 0 DNA Repair Proteins of the Nucleocapsid 0 Cell Cycle Regulator Proteins in the Nucleocapsid 0 Apoptosis Inhibitor Proteins in the Nucleocapsid 0 Nucleocapsid-Associated Proteins Involved in Transcriptional Activation 0 ODV Envelope and Tegument Proteins 0 ODV Proteins Interacting with the Tegument 0 ODV Envelope Proteins 0 ODV-E18, ODV-E35, and ODV-EC27 0 ODV-E66 and ODV-E25 0 Trafficking of ODV Envelope Proteins, FP25K and BV/ODV-E26 0 ODV-E56 0 P74 (PIF-0) 0 Proteases, P74, and Oral Infectivity 0 PIF-1 and PIF-2 0 PIF-3 and 11K Proteins 0 Summary of ODV Envelope Proteins 0 Conclusions 0 Acknowledgments 0 References 0 Coupling of Rotavirus Genome Replication and Capsid Assembly 0 Introduction 0 General Features of Rotavirus 0 Virion Architecture 0 Genome Coding Potential 0 Genome Sequences 0 Genome Rearrangement 0 Genome Reassortment 0 Replication Cycle 0 Viroplasms 0 NSP2 and NSP5 0 NSP4 0 RNA Localization 0 Replication Intermediates 0 Genome Replication 0 Replicase Activity 0 Initiation of Minus-Strand Synthesis 0 VP1 0 Cis-Acting Replication Signals 0 Perspectives 0 Acknowledgments 192 References 0 Origin and Evolution of 3'Utr of Flaviviruses: Long Direct Repeats as A Basis for the Formation of Secondary Structures and their Significance for Virus Transmission 201 Introduction 0 Short Direct Repeat Sequences 0 Flavivirus Secondary RNA Structures 0 What Is the Functional Significance of the DRs? 0 Evolution of the Flavivirus 3'UTR Occurred by Multiple Duplications 0 Alignment of the TBFV 3'UTRs 0 Alignment of the NCFV 3'UTRs 0 Alignment of the MBFV 3'UTRs 0 Alignment of the NKV 3'UTRs 0 DRs Might Serve Essential Functions for Viral Transmission 0 Alignment of All Flavivirus 3'UTRs 0 The MBFV Lost a Y-Shaped Structure 0 The CS2 and RCS2 of the MBFV and NKV and the Two Repeats of KRV and CFAV Might Represent Regions Equivalent to the TBFV LRS3 and LRS4 0 The Previously Nonaligned TBFV Region Aligns with the NCFV Alignment 0 The Region Containing Six R1 + R4 Repeats Is Unique to the TBFV Group 0 The RCS3 but Not the CS3 Aligns with the TBFV LRSs 0 The Poly-AT Region of the Flaviviruses Was Probably Present in the Earliest Flavivirus Lineages 0 Are the YFV Triple Repeat Sequences Present in the NCFV Group? 0 Evolution of the Flavivirus 3'UTR 0 Conclusions 0 References 0 Tropical Whitefly Ipm Project 0 Introduction 0 The Tropical Whitefly IPM Project 0 B. tabaci as a Vector of Viruses Affecting Cassava and Sweet Potato in Sub-Saharan Africa 0 Whitefly-Borne Viruses Affecting Cassava in East Africa 0 Whitefly-Borne Viruses Affecting Sweet Potato in East Africa 0 Whiteflies as Pests and Vectors of Plant Viruses in Sub-Saharan Africa 0 Socioeconomic Aspects Related to Whitefly-Related Problems in Sub-Saharan Africa 0 B. tabaci as a Vector of Viruses in Mixed Cropping Systems of Eastern Africa 0 Whiteflies as Vectors of Viruses in Mixed Cropping Systems in the Lowlands and Mid-Altitude Valleys of Mexico, Central America, and the Caribbean 0 The Whitefly Vector: B. tabaci 0 Collaborative IPM Activities on Whiteflies and Associated Viruses in Latin America 0 Trialeurodes vaporariorum as a Pest in Mixed Cropping Systems of the Andean Highlands 0 B. tabaci as a Vector of Viruses in Mixed Cropping Systems of Southern Asia 0 Whiteflies as Pests of Cassava in South America 0 Conclusions 0 Acknowledgments 0 References 0 Content: The Innate Antiviral Response: New Insights Into A Continuing Story Review Article Pages 1-66 Andrea Paun, Paula M. Pitha Apoptosis During Herpes Simplex Virus Infection Review Article Pages 67-97 Marie L. Nguyen, John A. Blaho The Baculoviruses Occlusion‐Derived Virus: Virion Structure and Function Review Article Pages 99-165 Jeffery Slack, Basil M. Arif Coupling of Rotavirus Genome Replication and Capsid Assembly Review Article Pages 167-201 John T. Patton, Rodrigo Vasquez‐Del Carpio, M. Alejandra Tortorici, Zenobia F. Taraporewala Origin and Evolution of 3′Utr of Flaviviruses: Long Direct Repeats as A Basis for the Formation of Secondary Structures and Their Significance for Virus Transmission Review Article Pages 203-248 T.S. Gritsun, E.A. Gould Tropical Whitefly IPM Project Review Article Pages 249-311 Francisco J. Morales Series Editors Page II Contents Pages V-VI Index Pages 313-321 Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology