Advances in Protein Chemistry, Volume 57: Prion Proteins (Advances in Protein Chemistry)

Prion Proteins is "issue-oriented" and edited by a well-known authority in the field. Topics covered include structure, diversity, and energetics as well as the diseases associated with prion proteins. Content: Preface Pages xi-xiii Byron Caughey Prion protein diversity and disease in the transmissible spongiform encephalopathies Review Article Pages 1-27 Suzette Apriola Mass spectrometric analysis of prion proteins Review Article Pages 29-54 Michael A. Baldwin Three-dimensional structures of prion proteins Review Article Pages 55-82 Kurt Wüthrich, Roland Riek Folding dynamics and energetics of recombinant prion proteins Review Article Pages 83-105 Rudi Glockshuber Simulations and computational analyses of prion protein conformations Review Article Pages 107-137 Darwin O.V. Alonso, Valerie Daggett Interactions and conversions of prion protein isoforms Review Article Pages 139-169 Byron Caughey, Gregory J. Raymond, Michael Acallahan, Cai'ne Wong, Gerald S. Baron, Liang-Wen Xiong Studies on peptide fragments of prion proteins Review Article Pages 171-201 Fabrizio Tagliavini, Gianluigi Forloni, Pasqualina D'Ursi, Orso Bugiani, Mario Salmona Biosynthesis and cellular processing of the prion protein Review Article Pages 203-228 David A. Harris Interaction of prion proteins with cell surface receptors, molecular chaperones, and other molecules Review Article Pages 229-272 Sabine Gauczynski, Christoph Hundt, Christoph Leucht, Stefan Weiss Transgenic studies of the influence of the PrP structure on TSE diseases Review Article Pages 273-311 Emmanuel A. Asante, John Collinge Yeast prions act as genes composed of self-propagating protein amyloids Review Article Pages 313-334 Reed B. Wickner, Kimberly L. Taylor, Herman K. Edskes, Marie-Lise Maddelein, Hiromitsu Moriyama, B.Tibor Roberts [ PSI + ], SUP35 , and chaperones Review Article Pages 335-366 Tricia Serio, Susan Lindquist Author index Pages 367-391 Subject index Pages 393-405 Prion protein diversity and disease in the transmissible spongiform encephalopathies -- Suzette A. Priola Mass spectometric analysis of prion proteins -- Michael A. Baldwin Three-dimensional structures of prion proteins -- Kurt Wüthrich and Roland Riek Folding dynamics and energetics of recombinant prion proteins -- Rudi Glockshuber Simulations and computational analyses of prion protein conformations -- Darwin O.V. Alonso and Valerie Daggett Interactions and conversions of prion protein isoforms -- Byron Caughey ... [et al.] Studies of peptide fragments of prion proteins -- Fabrizio Tagliavini ... [et al.] Biosynthesis and cellular processing of the prion protein -- David A. Harris Interaction of prion proteins with cell surface receptors, molecular chaperones, and other molecules -- Sabine Gauczynski ... [et al.] Transgenic studies of the influence of the PrP structure on TSE diseases -- Emmanuel A. Asante and John Collinge Yeast prions act as genes composed of self-propagating protein amyloids -- Reed B. Wickner ... [et al.] (PSIp+s), SUP35, and Chaperones-- Tricia R. Serio and Susan L. Lindquist. In the late 1970s, Great Britain altered the process by which animal carcasses were rendered to provide meat and bone meal protein supplements to sheep, cattle, and other livestock.