Advances in Protein Chemistry: Lipoproteins, Apolipoproteins, and Lipases (Advances in Protein Chemistry)

This volume contains eight chapters that present both new and reviewed information fundamental to a clear understanding of lipid catabolism and transport at the molecular level. Three-dimensional structures of important serum lipoproteins, apolipoproteins, and lipases, utilizing X-ray data when available, are emphasized, and an attempt is made to relate structures to function. Key Features * Amphipathic helix * Apolipoprotein E * Lipophorin * Structure of serum albumin * Lipid binding proteins * Apolipoprotein B * Low-density lipoprotein Content: Edited by Page iii Copyright page Page iv Contributors Pages ix-x Preface Pages xi-xvi Verne N. Schumaker Structure and Function of Lipases Original Research Article Pages 1-52 Zygmunt S. Derewenda Structure and Catalytic Mechanism of Secretory Phospholipases A 2 Original Research Article Pages 53-88 David L. Scott, Paul B. Sigler Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins Original Research Article Pages 89-151 Leonard Banaszak, Nathan Winter, Zhaohui Xu, David A. Bernlohr, Sandra Cowan, Alwyn T. Jones Structure of Serum Albumin Original Research Article Pages 153-176,176a,176b,176c,176d,176e,176f,176g,176h,176i,176j,176k,176l,177-203 Daniel C. Carter, Joseph X. Ho Apolipoprotein B and Low-Density Lipoprotein Structure: Implications for Biosynthesis of Triglyceride-Rich Lipoproteins Original Research Article Pages 205-248 Verne N. Schumaker, Martin L. Phillips, Jon E. Chatterton Apolipoprotein E: Structure-Function Relationships Original Research Article Pages 249-302 Karl H. Weisgraber The Amphipathic α Helix: A Multifunctional Structural Motif in Plasma Apolipoproteins Original Research Article Pages 303-369 Jere P. Segrest, David W. Garber, Christie G. Brouillette, Stephen C. Harvey, G.M. Anantharamaiah Lipophorin: The Structure of an Insect Lipoprotein and Its Role in Lipid Transport in Insects Original Research Article Pages 371-415 José L. Soulages, Michael A. Wells Author Index Pages 417-450 Subject Index Pages 451-459 Part of a series that presents the latest developments in protein chemistry, this volume covers topics including: low-density lipoproteins; apolipoprotein B; lipid binding proteins; the structure of serum albumin; lipophorin; apolipoprotein E; and the amphipathic helix.