Advances in Immunopharmacology 4: Proceedings of the Fourth International Conference on Immunopharmacology, Osaka, Japan, 16-19 May 1988 (Advances in Immunopharmacology)

The Fourth International Conference on Immunopharmacology took place in Osaka, Japan, May 1988. It was attended by over 900 participants from a variety of fields, illustrating the broad interest and wide-ranging applications of the subject. This Proceedings volume provides a comprehensive record of the Conference and is organized according to the sectional headings employed at the meeting. The topics covered include basic and clinical immunology, and preclinical and clinical aspects of immunopharmacology. The material presented is referenced and indexed throughout, and illustrated with photographs, diagrams and tables. Content: Previous Volumes in the Series , Page ii Front Matter , Page iii Copyright , Page iv Introduction and Overview on AIDS , Pages 3-10 , JOHN L. FAHEY, BO HOFMANN AIDS Vaccine Development—1988 , Pages 11-18 , ROBERT B. COUCH Current Immunotherapeutic Efforts and Future Prospects in Human HIV Disease , Pages 19-28 , JOHN W. HADDEN Experience in the Immunotoxicity Testing of Recombinant Cytokines , Pages 29-38 , YOSHIO HARADA Overview on Neuroimmunomodulation and a Possible Role for Serotonergic System , Pages 41-45 , K. MAŠEK A Molecular Basis for Bidirectional Communication between the Neuroendocrine and Immune Systems , Pages 47-54 , ERIC M. SMITH, EVE W. JOHNSON Enhancement of Mammalian Sleep by Immune Modulators , Pages 55-63 , J.M. KRUEGER, L.A. TOTH, L. JOHANNSEN, F. OBAL, M. OPP, A.B. CADY Physiological Roles of Histamine H 3 -Receptors , Pages 65-70 , J-M. ARRANG, M. GARBARG, J-C. LANCELOT, J-M. LECOMTE, H. POLLARD, M. ROBBA, W. SCHUNACK, J-C. SCHWARTZ Cell-Cell Contact- and Cytokine-controlled B Lymphocyte Responses and their Potential Influences in Hematopoiesis , Pages 73-80 , ANTONIUS ROLINK, MARTIN STREB, HAJIME KARASUYAMA, FRITZ MELCHERS The Colony Stimulating Factors: Discovery to Clinical Applications , Pages 81-86 , DONALD METCALF Characterization of the Mouse Interleukin 3 Receptor System , Pages 87-93 , ATSUSHI MIYAJIMA, HOLANDA SCHREURS, HUEY-MEI WANG, KAZUO MARUYAMA, DAN GORMAN, SHIGEO KOYASU, ICHIRO YAHARA, JEAN Y.J. WANG, YUMIKO OHTA, KEN-ICHI ARAI Interleukin-2 Receptor Targeted Immunosuppressive Therapy with Anti-Interleukin-2 Receptor Monoclonal Antibodies Directed against the L-Chain of the Interleukin-2 Receptor: Studies on Selectivity and Mode of Action , Pages 95-104 , T. DIAMANTSTEIN, N.L. TILNEY, J.W. KUPIEC-WEGLINSKI, T. STROM, H.P. VAN DER MEIDE, H.J. HAHN, H-D. VOLK, A.P. WEETMAN Efficacy of Low-dose Cyclophosphamide and Interleukin-2 in Melanoma , Pages 105-118 , MALCOLM S. MITCHELL, RAYMOND A. KEMPF, WILLIAM HAREL, HUNGYI SHAU, WILLIAM D. BOSWELL, SUSAN LIND, GRACE DEAN, JANE MOORE, EDWARD C. BRADLEY Anti-idiotype Modeled Peptides with Biologic Activity , Pages 119-126 , W.V. WILLIAMS, D.A. MOSS, D.B. WEINER, J.A. COHEN, H.R. GUY, M.I. GREENE Pharmacokinetics and Organ Targeting of Monoclonal Antibodies , Pages 127-129 , K. FUJIMORI, J.N. WEINSTEIN Modulation of the Immunogenic Characters of Protective Epitopes in Synthetic Vaccines , Pages 133-142 , F. AUDIBERT, C. JOLIVET-REYNAUD, M. JOLIVET, D. LISE Current Status of Malaria Vaccines: The Need for Safe and Effective Adjuvants , Pages 143-147 , W.A. SIDDIQUI, L.Q. TAM Immunoadjuvants for Vaccine , Pages 149-158 , I. AZUMA, Y. YAMAMURA Interleukin 6 and its Receptor: Pathological Role in Autoimmunity and Lymphoid Malignancy , Pages 161-168 , T. HIRANO, T. TAGA, K. YAMASAKI, T. MATSUDA, B. TANG, S. SUEMATSU, Y. HORII, Y. HIRATA, H. YAWATA, A. MURAGUCHI, T. KISHIMOTO, M. KAWANO, N. MIYASAKA, M. SHIMIZU The Hybridoma/Plasmacytoma Growth Factor (HPGF) Activity of IL-6. Stimulation of its Secretion by Different Inducers in Various Cell Types , Pages 169-174 , J. VAN DAMME°, G. OPDENAKKER°, J. VAN SNICK, B. DECOCK, J.-P. LENAERTS, W. PUT, A. BILLIAU Interferon-type and Other Activities of IFN-ß-2/BSF-2/HSF , Pages 175-183 , M. REVEL, L. CHEN, Y. MORY, A. ZILBERSTEIN, R. MICHALEVICZ Interleukin-6: Biological Function and Regulation of the Gene Expression in Vitro and in Vivo , Pages 185-190 , W. FIERS, P. BROUCKAERT, R. CONTRERAS, B. EVERAERDT, Y. GUISEZ, C. LIBERT, N. TAKAHASHI, B. TISON, P. VANDENABEELE, J. CONTENT, D. SPRIGGS, J. VAN SNICK Interleukin-6 is the Major Regulator of Acute Phase Protein Synthesis in Rat and Man , Pages 191-201 , J.V. CASTELL, M. DAVID, J. KLAPPROTH, P.C. HEINRICH, T. ANDUS, T. GEIGER, M. GÓMEZ-LECHÓN, T. HIRANO, T. KISHIMOTO The Role of Kinase Activation and Gene Expression in the Action of Interleukin 2 , Pages 205-209 , WILLIAM L. FARRAR, ANNICK HAREL-BELLAN, DOUGLAS K. FERRIS Transmembrane Events in Mast Cell Histamine Release , Pages 211-217 , TERUKO ISHIZAKA An Approach to the Mode of Action of Lipocortins , Pages 219-222 , BERNARD ROTHHUT, CHRISTINE COMÉRA, FRANÇLOISE RUSSO-MARIE Protein Kinase C and Signal Transduction in T Lymphocytes , Pages 223-230 , N. BERRY, K. ASE Regulation of Human Eosinophil Phenotype , Pages 231-237 , M.E. ROTHENBERG, K.F. AUSTEN Bacteria and Natural Products as Immunomodulators (II) , Pages 241-243 , M.A. PARANT, H. TAKADA Bacteria and Natural Products as Immunomodulators (III) , Pages 245-250 , T. TOKUNAGA, S. TSUNG-TANG Glucans and Immunomodifiers (I) , Pages 251-253 , J.K. CZOP, G. CHIHARA Glucans and Immunomodifiers (II) , Pages 255-257 , K. NOEL MASIHI, SHIGEO SUZUKI Synthetic Immunomodifiers (I) , Pages 259-262 , I. AZUMA, G. RENOUX Synthetic Immunomodifiers (II) , Pages 263-265 , MICHAEL A. CHIRIGOS, TETSUO SHIBA Lymphokines and Monokines (I) , Pages 267-268 , KEN-ICHI ARAI, TOSHIO HIRANO Lymphokines and Monokines (II) , Pages 269-271 , D.R. WEBB, I. YAHARA Thymic Hormones , Pages 273-275 , H. ISHITSUKA, G. DORIA Effector Functions of Cytokines in Cancer , Pages 277-280 , E. LOTZOVÁ, E. TSUBURA Clinical Applications of Cytokines , Pages 281-283 , M.S. MITCHELL, N. OHSAWA Summary MDP and Derivatives , Pages 285-287 , H. FROST, S. KOTANI Allergy and Antiallergies , Pages 289-290 , A.L. DE WECK, T. MIYAMOTO Pharmacology of Immunocytes , Pages 291-294 , JEAN-FRANCOIS PETIT, TAKESHI OGURA Immunotoxicology , Pages 295-297 , ENRICO MIHICH, KEIJI UDAKA Novel Aspects and Approaches in Immunomanipulation , Pages 299-300 , A.C. ALLISON, T. TADA Immune Manipulation in Infectious Diseases , Pages 301-302 , A.G. JOHNSON, K. NOMOTO Novel Vaccines , Pages 303-305 , A. OYA, F. AUDIBERT Immunosuppressive Agents (I) Deoxyspergualin and Other Interesting Agents , Pages 307-310 , H. AMEMIYA, J.E. TALMADGE Immunosuppressive Agents (II) , Pages 311-314 , P.C. HIESTAND, T. OCHIAI Endotoxins , Pages 315-316 , T.W. KLEIN, M. NAKANO Drug Delivery Systems Including Liposomes as Carriers , Pages 317-319 , CARL R. ALVING, YOSHIYUKI HASHIMOTO Immunomodulatory Effects of Traditional Medicines , Pages 321-324 , CHAO WEIKANG, SEIJI MORISAWA Author Index , Pages 325-326 Subject Index , Pages 327-328