Advances in Immunology, Vol. 100 : Immunopathogenesis of Type 1 Diabetes Mellitus [ISBN : 9780123743268] [Copyright Year : 2008] [Hardcover]

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. This thematic volume focuses on the immunopathogenesis of type 1 diabetes mellitus. Edited and authored by the foremost scientists in this field, it provides up-to-date information and directions for future research. Content: Series Editors Page ii Copyright Page Page iv Contributors to Volume 100 Pages ix-xi Chapter 1 Autoimmune Diabetes Mellitus—Much Progress, but Many Challenges Review Article Pages 1-12 Hugh O. McDevitt, Emil R. Unanue Chapter 2 CD3 Antibodies as Unique Tools to Restore Self-Tolerance in Established Autoimmunity: Their Mode of Action and Clinical Application in Type 1 Diabetes Review Article Pages 13-37 Sylvaine You, Sophie Candon, Chantal Kuhn, Jean-François Bach, Lucienne Chatenoud Chapter 3 GAD65 Autoimmunity—Clinical Studies Review Article Pages 39-78 Raivo Uibo, Åke Lernmark Chapter 4 CD8+ T Cells in Type 1 Diabetes Review Article Pages 79-124 Sue Tsai, Afshin Shameli, Pere Santamaria Chapter 5 Dysregulation of T Cell Peripheral Tolerance in Type 1 Diabetes Review Article Pages 125-149 Roland Tisch, Bo Wang Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes Review Article Pages 151-175 William M. Ridgway, Laurence B. Peterson, John A. Todd, Dan B. Rainbow, Barry Healy, Oliver S. Burren, Linda S. Wicker Index Pages 177-180 Contents of Recent Volumes Pages 181-186 Eight cutting-edge reviews on the immunopathogenesis of type 1 diabetes mellitus