Advances in Genetics, Vol. 61 : Long-Range Control of Gene Expression [ISBN : 9780123738813] [Copyright Year : 2008]

This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. * Includes information on aspergillus genomes * Discusses sex and its role in virulence of human fungal pathogens * Covers the genomic analysis of neurospora Jack R. Girton and Kristen M. Johansen Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei -- Bernhard Horsthemke and Karin Buiting Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei -- Bernhard Horsthemke and Karin Buiting -- Esteban Ballestar and Manel Esteller Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei -- Bernhard Horsthemke and Karin Buiting -- Esteban Ballestar and Manel Esteller -- Gabriela G. Loots Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei -- Bernhard Horsthemke and Karin Buiting -- Esteban Ballestar and Manel Esteller -- Gabriela G. Loots -- Emmanouil T. Dermitzakis Jack R. Girton and Kristen M. Johansen -- Julio Mateos-Langerak and Giacomo Cavalli -- Pat Simpson and Savita Ayyar -- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld -- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood -- Francois Spitz and Denis Duboule -- Le-Ben Wan and Marisa S. Bartolomei -- Bernhard Horsthemke and Karin Buiting -- Esteban Ballestar and Manel Esteller -- Gabriela G. Loots -- Emmanouil T. Dermitzakis -- Adam Woolfe and Greg Elgar Jack R. Girton and Kristen M. Johansen-- Julio Mateos-Langerak and Giacomo Cavalli-- Pat Simpson and Savita Ayyar-- Robert-Jan Palstra, Wouter de Laat, and Frank Grosveld-- Douglas R. Higgs, Douglas Vernimmen, and Bill Wood-- Francois Spitz and Denis Duboule-- Le-Ben Wan and Marisa S. Bartolomei-- Bernhard Horsthemke and Karin Buiting-- Esteban Ballestar and Manel Esteller-- Gabriela G. Loots-- Emmanouil T. Dermitzakis-- Adam Woolfe and Greg Elgar-- Dirk A. Kleinjan and Laura A. Lettice. Content: Contributors to Volume 61 Pages XI-XII Preface Pages XIII-XV Robert E. Hill, Veronica van Heyningen Chapter 1 Chromatin Structure and the Regulation of Gene Expression: The Lessons of PEV in Drosophila Review Article Pages 1-43 Jack R. Girton, Kristen M. Johansen Chapter 2 Polycomb Group Proteins and Long‐Range Gene Regulation Review Article Pages 45-66 Julio Mateos‐Langerak, Giacomo Cavalli Chapter 3 Evolution of Cis‐ Regulatory Sequences in Drosophila Review Article Pages 67-106 Pat Simpson, Savita Ayyar Chapter 4 β‐Globin Regulation and Long‐Range Interactions Review Article Pages 107-142 Robert‐Jan Palstra, Wouter de Laat, Frank Grosveld Chapter 5 Long‐Range Regulation of α‐Globin Gene Expression Review Article Pages 143-173 Douglas R. Higgs, Douglas Vernimmen, Bill Wood Chapter 6 Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution Review Article Pages 175-205 Francois Spitz, Denis Duboule Chapter 7 Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators Review Article Pages 207-223 Le‐Ben Wan, Marisa S. Bartolomei Chapter 8 Genomic Imprinting and Imprinting Defects in Humans Review Article Pages 225-246 Bernhard Horsthemke, Karin Buiting Chapter 9 Epigenetic Gene Regulation in Cancer Review Article Pages 247-267 Esteban Ballestar, Manel Esteller Chapter 10 Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis Review Article Pages 269-293 Gabriela G. Loots Chapter 11 Regulatory Variation and Evolution: Implications for Disease Review Article Pages 295-306 Emmanouil T. Dermitzakis Chapter 12 Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes Review Article Pages 307-338 Adam Woolfe, Greg Elgar Chapter 13 Long‐Range Gene Control and Genetic Disease Review Article Pages 339-388 Dirk A. Kleinjan, Laura A. Lettice Index Pages 389-399 Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced.

* Discusses the evolution of cis-regulatory sequences in drosophila
* Includes information on genomic imprinting and imprinting defects in humans
*Includes a chapter on epigenetic gene regulation in cancer The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines Covers the progress in understanding the mechanisms for genomic control of gene expression. This book includes information on aspergillus genomes. It discusses sex and its role in virulence of human fungal pathogens. It also covers the genomic analysis of neurospora