Advances in Clinical Chemistry, Volume 43 (Advances in Clinical Chemistry) (Advances in Clinical Chemistry)

Volume forty-three of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. In this volume, the biochemistry of bilirubin, the endproduct of heme metabolism, is explored with respect to its potential beneficial role in preventing oxidative changes associated with a variety of pathological conditions including atherosclerosis, cancer, inflammatory, autoimmune and other degenerative diseases. Content: The Heme Catabolic Pathway and its Protective Effects on Oxidative Stress‐Mediated Diseases Review Article Pages 1-57 Libor Vítek, Harvey A. Schwertner Cyclooxygenase‐2 and Tumor Biology Review Article Pages 59-78 Shigeru Kanaoka, Tetsunari Takai, Ken‐ichi Yoshida Oligonucleotide Probes for RNA‐Targeted Fluorescence In Situ Hybridization Review Article Pages 79-115 Adam P. Silverman, Eric T. Kool Activin A In Brain Injury Review Article Pages 117-130 Pasquale Florio, Diego Gazzolo, Stefano Luisi, Felice Petraglia Methods for Predicting Human Drug Metabolism Review Article Pages 131-176 Larry J. Jolivette, Sean Ekins A Summary Analysis of Down Syndrome Markers in the Late First Trimester Review Article Pages 177-210 Glenn E. Palomaki, Geralyn M. Lambert‐Messerlian, Jacob A. Canick Estrogen Hydroxylation in Osteoporosis Review Article Pages 211-227 Nicola Napoli, Reina Armamento‐Villareal Cytochrome P450: Another Player in the Myocardial Infarction Game? Review Article Pages 229-280 Raute Sunder‐Plassmann Contents Pages V-VII Contributors to Volume 43 Pages IX-X Preface Page XI Gregory S. Makowski Index Pages 281-288 Volume 43 of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. In this volume, the biochemistry of bilirubin, the end-product of heme metabolism, is explored with respect to its potential beneficial role in preventing oxidative changes associated with a variety of pathological conditions, including atherosclerosis, cancer, and inflammatory, autoimmune and other degenerative diseases. Explores the biochemistry of bilirubin, the end-product of heme metabolism with respect to its potential beneficial role in preventing oxidative changes associated with a variety of pathological conditions including atherosclerosis, cancer, inflammatory, autoimmune and other degenerative diseases. Emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies. This title contains chapters submitted from some of the leading experts from academia and clinical laboratory science.