Advances in Bioinformatics and Computational Biology: 4th Brazilian Symposium on Bioinformatics, BSB 2009, Porto Alegre, Brazil, July 29-31, 2009, Proceedings (Lecture Notes in Computer Science, 5676)

This book constitutes the refereed proceedings of the 4th Brazilian Symposium on Bioinformatics, BSB 2009, held in Porto Alegre, Brazil, in July 2009 The 12 revised full papers and 6 extended abstracts were carefully reviewed and selected from 55 submissions. The papers are organized in topical sections on algorithmic approaches for molecular biology problems; micro-array analysis; machine learning methods for classification; and in silico simulation. Front Matter....Pages - Genotype Tagging with Limited Overfitting....Pages 1-12 Constraint Programming Models for Transposition Distance Problem....Pages 13-23 Comparison of Spectra in Unsequenced Species....Pages 24-35 BiHEA: A Hybrid Evolutionary Approach for Microarray Biclustering....Pages 36-47 Using Supervised Complexity Measures in the Analysis of Cancer Gene Expression Data Sets....Pages 48-59 Quantitative Improvements in cDNA Microarray Spot Segmentation....Pages 60-72 SOM-PORTRAIT: Identifying Non-coding RNAs Using Self-Organizing Maps....Pages 73-85 Automatic Classification of Enzyme Family in Protein Annotation....Pages 86-96 Representations for Evolutionary Algorithms Applied to Protein Structure Prediction Problem Using HP Model....Pages 97-108 Comparing Methods for Multilabel Classification of Proteins Using Machine Learning Techniques....Pages 109-120 Comparative Study of Classification Algorithms Using Molecular Descriptors in Toxicological DataBases....Pages 121-132 Influence of Antigenic Mutations in Time Evolution of the Immune Memory – A Dynamic Modeling....Pages 133-142 FReDD: Supporting Mining Strategies through a Flexible-Receptor Docking Database....Pages 143-146 A Wide Antimicrobial Peptides Search Method Using Fuzzy Modeling....Pages 147-150 Identification of Proteins from Tuberculin Purified Protein Derivative (PPD) with Potential for TB Diagnosis Using Bioinformatics Analysis....Pages 151-155 Mapping HIV-1 Subtype C gp120Epitopes Using a Bioinformatic Approach....Pages 156-159 MHC: Peptide Analysis: Implications on the Immunogenicity of Hantaviruses’ N protein....Pages 160-163 An Ontology to Integrate Transcriptomics and Interatomics Data Involved in Gene Pathways of Genome Stability....Pages 164-167 Back Matter....Pages - This volume contains the papers selected for presentation at the 4th Brazilian Sym- sium on Bioinformatics, BSB 2009, which was held in Porto Alegre, Brazil, during August 29–31, 2009. The BSB symposium had its origins in the Brazilian Workshop on Bioinformatics (WOB). WOB had three editions, in 2002 (Gramado, RS), in 2003 (Macaé, RJ), and in 2004 (Brasília, DF). The change in the designation from wo- shop to symposium reflects the increase in the quality of the contributions and also in the interest of the scientific community for the meeting. The previous editions of BSB took place in São Leopoldo, RS, in 2005, in Angra dos Reis, RJ, in 2007, and in Santo André, SP, in 2008. As evidence of the internationalization of the event, BSB 2009 had 55 submissions from seven countries. Of the 55 papers submitted, 36 were full papers, with up to 12 pages each, and 19 were extended abstracts, with up to 4 pages each. The articles submitted were carefully reviewed and selected by an international Program Comm- tee, comprising three chairs and 45 members from around the world, with the help of 21 additional reviewers. The Program Committee Chairs are very thankful to the - thors of all submitted papers, and especially to the Program Committee members and the additional reviewers, who helped select the 12 full papers and the six extended abstracts that make up this book.