Adult In Leukemias 1 (cancer Treatment And Research) (v. 1)

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and pub­ lished symposium lectures are often the best overviews available. Unfortu­ nately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by di­ viding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco­ logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre­ quently publish good indepth reviews of cancer topics, and published sympo­ sium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid­ ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the Specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor­ tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagno­ sis, staging, markers, all forms of treatment modalities, basic biology, and more. Where do you begin to look for arecent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco­ logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre­ quently publish good in-depth reviews of cancer topics, and published sym­ posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is aseries of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. Wehave approached the problem in the following fashion. First, by divid­ ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, supportive care, etc. Second, by asking eminent autho­ rities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Front Matter....Pages I-XII Viruses and Adult Leukemia — Lymphoma of Man and Relevant Animal Models....Pages 1-41 T-cell Growth Factor-Dependent Leukemic Cell Growth: Therapeutic Implications....Pages 43-60 Treatment related leukemia....Pages 61-108 The French-American-British Classification of the Acute Adult Myeloid Leukemias: Its Clinical Relevance....Pages 109-125 Chromosome Abnormalities in Adult Acute Leukemia: Biologic and Therapeutic Significance....Pages 127-153 An Integrated Approach to the Study and Treatment of Acute Myelocytic Leukemia....Pages 155-197 Acute Nonlymphocytic Leukemia in the Elderly: Biology and Treatment....Pages 199-235 Early Identification of Potentially Cured Patients with Acute Myelogenous Leukemia — A Recent Challenge....Pages 237-263 The Clinical Relevance of Lymphocyte Surface Markers in Adult Acute Lymphoblastic Leukemia....Pages 265-308 The Therapy of Adult Acute Lymphoblastic Leukemia....Pages 309-349 The Role of Therapeutic and Prophylactic Granulocyte Transfusions in Adult Acute Leukemia....Pages 351-380 Bone Marrow Transplantation in Adult Acute Leukaemia: Who Should Be Transplanted, and When?....Pages 381-406 Back Matter....Pages 407-415 Pulmonary cacinogenesis / Theodore L. McLemore, R. Russell Martin Adjuvant therapy with surgery / William P. McGuire The immunotherapy of lung cancer / E. Carmack Holmes The use of pre-operative radiation therapy in the treatment of lung carcinoma / David M. Sherman, Ralph R. Weichselbaum Lung cancer-post resection irradiation / Nathan Green The role of radiation therapy in the treatment of regional non-small (oat)-cell carcinoma of the lung / Joel Eliot White, Murray Boles Small cell anaplastic carcinoma of the lung / Heine H. Hansen, Per Dombernowsky Small cell bronchogenic carcinoma / Paul A. Bunn, Jr., Daniel C. Ihde Radiation therapy-new approaches / Omar M. Salazar, Gunar Zagars Pathology of small cell carcinoma of the lung and its subtypes / Mary J. Matthews, Adi F. Gazdar. However, despite optimal treatment with surgery and radiotherapy, patients with nodal spread or extensive local disease have a low cure rate. New, creative methods of radiation therapy delivery, such as the use of multiple fractions per day, as discussed by Parsons and Million, are also contributing to long-term local control.