Adjuvant Therapy for Breast Cancer (Cancer Treatment and Research Book 151)

Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable. "The adjuvant treatment of breast cancer has become standard of care. A spectrum of biologic and prognostic factors are considered before a therapeutic strategy is implemented. In this text leading investigators in the field discuss current management and critical investigative issues." Steven T. Rosen, M.D. Series Editor Front Matter....Pages i-xvi Front Matter....Pages 1-1 History of Adjuvant Therapy....Pages 3-12 Prognostic and Predictive Factors....Pages 13-30 New Perspectives for Therapy Choice....Pages 31-40 Pathology Role in Adjuvant Setting....Pages 41-61 Guidelines, Consensus Conferences and Overviews (Meta-analysis)....Pages 63-76 Statistical Issues and Challenges....Pages 77-90 Front Matter....Pages 91-91 Multidisciplinary Care: Optimising Team Performance....Pages 93-101 Preoperative Chemo- and Endocrine Therapy....Pages 103-120 Adjuvant Chemotherapy....Pages 121-137 Postoperative Endocrine Therapy for Invasive Breast Cancer....Pages 139-161 Adjuvant Therapy of Breast Cancer – Bisphosphonates....Pages 163-177 Front Matter....Pages 179-179 Trastuzumab....Pages 181-196 Lapatinib: New Directions in HER2 Directed Therapy for Early Stage Breast Cancer....Pages 197-215 Front Matter....Pages 217-217 Supportive Care During Adjuvant Treatment....Pages 219-238 Dose in (Adjuvant) Chemotherapy of Breast Cancer....Pages 239-253 Timing of Adjuvant Therapy....Pages 255-279 Sequencing of Systemic Treatment and Radiotherapy....Pages 281-287 Front Matter....Pages 289-289 Young Patients with Breast Cancer....Pages 291-298 Special Populations: Elderly Patients....Pages 299-315 Adjuvant Therapy in Patients with Breast Cancer During Pregnancy....Pages 317-328 Front Matter....Pages 329-329 Investigations After Adjuvant Therapy....Pages 331-352 Quality of Life Issues During Adjuvant Endocrine Therapy....Pages 353-365 Fertility....Pages 367-385 Cognitive Function in Breast Cancer Survivors....Pages 387-419 Costs of Adjuvant Breast Cancer Treatments....Pages 421-440 Social Issues: Marital Support....Pages 441-450 The View and Role of Breast Cancer Advocacy....Pages 451-459 The Voice of a Special Patient....Pages 461-466 Back Matter....Pages 467-490 Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. It has proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence