Adenomatous Polyps of the Colon : Pathobiological and Clinical Features

Adenomatous Polyps of the Colon: Pathobiological and Clinical Features consolidates the vast body of basic science and clinical data associated with adenomatous polyps of the colon, much of it inspired by the realization that most colorectal carcinomas seem to arise in such polyps. This book strives to evaluate these data, with particular emphasis on their implications for management of polyp-bearing subjects. Topics comprehensively explored include anatomy and histology of the normal colon; pathologic characteristics of adenomatous polyps, differential diagnosis, and grading schemes for degree of dysplasia and villosity; adenomatous polyposes; histologic and epidemiologic evidence for the malignant potential of adenomatous polyps; and detection and management, with special attention to endoscopy, endoscopic polypectomy, the malignant polyp, and post-polypectomy surveillance schedules. Front Matter....Pages I-XVII Normal Colon....Pages 1-4 Pathology....Pages 5-44 Adenomatous Polyposes....Pages 45-52 Malignant Potential of Adenomatous Polyps....Pages 53-89 Detection and Management....Pages 90-127 Conclusions....Pages 128-129 Back Matter....Pages 130-136