Acute Kidney Injury - Scientific Evidence Driving Change in Patient Management (Nephron Vol. 109, No. 4)

The field of acute-care nephrology has recently seen significant changes, affecting the definition and classification of acute kidney dysfunction as well as our understanding of its epidemiology, the ability to make earlier diagnoses, the use of novel imaging modalities, and the insight into why acute kidney injury might occur under different clinical circumstances. Different experts have contributed to this issue, emphasizing the importance of the change of concept from that of acute renal failure to that of acute kidney injury.This change has led to the development of new definitions and classifications which, together with the understanding that even minor sub clinical injury to the kidney may matter, emphasize the need to develop early biomarkers. Sufficiently early diagnosis, a better classification system and a clearer understanding of the pathogenesis promise to deliver novel and effective therapies for patients. Summarizing recent developments, this publication will be an indispensable help for the clinician to determine the best treatment options for his patients. 109.04.I......Page 1 109.04.c181......Page 4 109.04.c182......Page 5 109.04.c188......Page 11 109.04.c192......Page 15 109.04.c198......Page 21 109.04.p55......Page 28 109.04.e95......Page 34 109.04.p61......Page 40 109.04.p73......Page 52 109.04.e102......Page 59 109.04.c206......Page 65 109.04.e109......Page 76 109.04.p80......Page 85 109.04.p85......Page 90 109.04.e118......Page 97 109.04.c217......Page 102 109.04.c224......Page 109 109.04.c229......Page 114 109.04.c230......Page 115 109.04.c231......Page 116 109.04.c234......Page 119 109.04.after_c236......Page 122 The field of acute-care nephrology has seen significant changes, affecting the definition and classification of acute kidney dysfunction as well as our understanding of its epidemiology. This book emphasizes the importance of the change of concept from that of acute renal failure to that of acute kidney injury.