Acetylcholine;: An approach to the molecular mechanism of action, (International series of monographs in pure and applied biology. Division: Modern trends in physiological sciences)

Acetylcholine: An Approach to the Molecular Mechanism of Action is an in-depth study of neurotransmitter system, with much focus on acetylcholine and its action and the cholinergic synapse. The book, divided into seven chapters, covers the following topics: the function of the cholinergic synapse; the movement of ions across membranes; the excitatory postsynaptic potential; the nature of cholinoreceptors and cholinesterases; the structure of its active centers; and the pattern of arrangement of the receptors of the cholinoreceptive membrane. The book also covers the quantitative evaluation of the action of neurotransmitters; the reactive capacity of the acetylcholine molecule and its effects on nerve endings and nerve fibers; and the release of mediators and hormones. The text is recommended for those who specialize in the fields of biology, medicine, biochemistry, and pharmacology, especially those wish to study about the neurotransmitter system, cholinoreceptors, the cholinergic synapse, the acetylcholine, and its action. Content: Front Matter, Page iii Copyright, Page iv Dedication, Page v Foreword, Pages ix-x Preface, Pages xi-xv Acknowledgements, Pages xvii-xviii CHAPTER 1 - The Function of the Cholinergic Synapse, Pages 1-4,4a,5-18,18a,19-32 CHAPTER 2 - The Nature of Cholinoreceptors and Cholinesterases and Methods of Study of their Chemical Structure, Pages 33-44 CHAPTER 3 - The Quantitative Evaluation of the Action of Substances that Stimulate and Block the Cholinoreceptor, Pages 45-72,72a CHAPTER 4 - The Reactive Capacity of the Acetylcholine Molecule and the Structure of the Active Centres of Cholinoreceptors and Cholinesterases, Pages 73-123 CHAPTER 5 - Patterns of Arrangement of Individual Receptors on the Cholinoreceptive Membrane, Pages 125-132,132a,133-154,154a,155-159 CHAPTER 6 - Changes in the Pattern of Arrangement of Cholinoreceptors in the Process of Evolution, Pages 161-174,174a,174b,175-186 CHAPTER 7 - Non-Synaptic Cholinoreceptors, Pages 187-198,198a,199-201 References, Pages 203-228 Author Index, Pages 229-235 Subject Index, Pages 237-241 Other Titles in the Division Modern Trends in Physiological Sciences, Page 243 By M. J. Michelson And E. V. Zeimal. Translated From The Russian By E. Lesser And Mira Lesser. Translation Of At︠s︡etilkholin. Bibliography: P. 203-228.