A symposium on mechanisms of toxicity : [held on April 13th-14th, 1970 in the Edward Lewis Theatre, the Middlesex Hospital Medical School, London

The symposium was organized by a Committee consisting of W. N. Front Matter....Pages i-xiii Front Matter....Pages 1-1 Inhibition Patterns of Monoamine Oxidase Isoenzymes: Clinical Implications....Pages 3-11 Monoamine Oxidases and Their Inhibitors....Pages 13-27 Some New Effects of Anticholinesterases in the Whole Animal, with Special Emphasis on the Hypothermia Inducing Action in the Rat....Pages 29-41 Mechanism of Inhibition of Glutamine Synthetase by Methionine Sulphoximine....Pages 43-63 Front Matter....Pages 65-65 Effect of Lathyrogenic Compounds on the Cross-Linking of Collagen and Elastin in Vivo....Pages 67-85 The Capacity of Aspirin to Acetylate Proteins in Vitro and in Vivo....Pages 87-102 Role of Immune Reactions in Response to Toxic Metals....Pages 103-110 Binding of Beryllium to Proteins....Pages 111-125 Front Matter....Pages 126-126 Liver Cell Injury by Beryllium....Pages 129-145 Ribonucleic Acid Polymerase in Nuclear Damage....Pages 147-161 Cell Suicide and Cell Death....Pages 163-173 Amoeba Proteus as a Cell Model in Toxicology....Pages 175-186 Front Matter....Pages 189-189 Antimetabolic Action of 6-Aminonicotinamide on the Pentose Phosphate Pathway in the Brain....Pages 189-203 Mode of Action of Hypoglycin and Related Compounds....Pages 205-218 Conversion by the Liver of Inactive Molecules into Toxic Molecules....Pages 219-228 The Role of the Gut Flora in the Conversion of Inactive Compounds to Active Metabolites....Pages 229-247 Back Matter....Pages 249-257