A Life of Ernest Starling (People and Ideas Series)

Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his “Law of the Heart,” but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins. Starling’s contributions include: *Developing the "Frank-Starling Law of the Heart," presented in 1915 and modified in 1919. *The Starling equation, describing fluid shifts in the body (1896) *The discovery of secretin, the first hormone, with Bayliss (1902) and the introduction of the concept of hormones (1905). Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his Law of the Heart, but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins. Starlings contributions include: *Developing the "Frank-Starling Law of the Heart," presented in 1915 and modified in 1919. *The Starling equation, describing fluid shifts in the body (1896) *The discovery of secretin, the first hormone, with Bayliss (1902) and the introduction of the concept of hormones (1905) Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his Law of the Heart, but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins.Starling s contributions *Developing the "Frank-Starling Law of the Heart," presented in 1915 and modified in 1919.*The Starling equation, describing fluid shifts in the body (1896)*The discovery of secretin, the first hormone, with Bayliss (1902) and the introduction of the concept of hormones (1905). "Starling was much more than a gifted scientist. He held passionate views on many subjects - education, the medical establishment, London University, Germany, the British Government - and was not slow to voice them. Time has shown most of his views to be right, but their publication certainly hampered his worldly success. Working on defense against poison gas during WWI, he crossed swords with the war office. After resigning his commission as colonel, he became chairman of the committee supervising British nutrition and successfully introduced food rationing. Prodigiously energetic, he also designed and developed the medical school at University College."--Jacket "Ernest Starling (1866-1927) was a preeminent figure in the golden age of British physiology. His name is usually associated with his Law of the Heart, but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word "hormone" one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall - an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins."