9th International Conference on Practical Applications of Computational Biology and Bioinformatics (Advances in Intelligent Systems and Computing Book 375)

This proceedings presents recent practical applications of Computational Biology and Bioinformatics. It contains the proceedings of the 9th International Conference on Practical Applications of Computational Biology & Bioinformatics held at University of Salamanca, Spain, at June 3rd-5th, 2015. The International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB) is an annual international meeting dedicated to emerging and challenging applied research in Bioinformatics and Computational Biology. Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next generation sequencing technologies, together with novel and ever evolving distinct types of omics data technologies, have put an increasingly complex set of challenges for the growing fields of Bioinformatics and Computational Biology. The analysis of the datasets produced and their integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Clearly, Biology is more and more a science of information requiring tools from the computational sciences. Front Matter....Pages i-xiii A Preliminary Assessment of Three Strategies for the Agent-Based Modeling of Bacterial Conjugation....Pages 1-9 Carotenoid Analysis of Cassava Genotypes Roots (Manihot Esculenta Crantz) Cultivated in Southern Brazil Using Chemometric Tools....Pages 11-18 UV-Visible Scanning Spectrophotometry and Chemometric Analysis as Tools to Build Descriptive and Classification Models for Propolis from Southern Brazil....Pages 19-27 UV-Visible Spectrophotometry-Based Metabolomic Analysis of Cedrela Fissilis Velozzo (Meliaceae) Calluses - A Screening Tool for Culture Medium Composition and Cell Metabolic Profiles....Pages 29-36 An Integrated Computational Platform for Metabolomics Data Analysis....Pages 37-47 Compound Identification in Comprehensive Gas Chromatography—Mass Spectrometry-Based Metabolomics by Blind Source Separation....Pages 49-57 Dolphin 1D: Improving Automation of Targeted Metabolomics in Multi-matrix Datasets of \(^1\) H-NMR Spectra....Pages 59-67 A New Dimensionality Reduction Technique Based on HMM for Boosting Document Classification....Pages 69-77 Diagnostic Knowledge Extraction from MedlinePlus: An Application for Infectious Diseases....Pages 79-87 A Text Mining Approach for the Extraction of Kinetic Information from Literature....Pages 89-98 A Novel Search Engine Supporting Specific Drug Queries and Literature Management....Pages 99-106 Identification of a Putative Ganoderic Acid Pathway Enzyme in a Ganoderma Australe Transcriptome by Means of a Hidden Markov Model....Pages 107-115 A New Bioinformatic Pipeline to Address the Most Common Requirements in RNA-seq Data Analysis....Pages 117-125 Microarray Gene Expression Data Integration: An Application to Brain Tumor Grade Determination....Pages 127-135 Obtaining Relevant Genes by Analysis of Expression Arrays with a Multi-agent System....Pages 137-146 Erratum to: Diagnostic Knowledge Extraction from MedlinePlus: An Application for Infectious Diseases....Pages E1-E1 Back Matter....Pages 147-148